Form 4 Biology national exam 2022 with answers
The 2022 Form 4 national exam paper for Form 4 Biology, question by question. Take it timed like the real exam, then see the answer and explanation to every question.
- 51 questions, 100 marks
- 120 minutes
Take this paper
120 minutes, 100 marks. Multiple choice is marked for you; you mark your written answers against the marking points.
A free account is needed to start, so your answers and results are saved.
Instructions to candidates
Answer all questions in the ANSWER BOOKLET.
Part I: Circle the letter of the correct answer (40 Marks)
- 12 marks
The structural and functional unit of nervous system is:
- A.Neurons
- B.Neurotransmitter
- C.Neuroglia
- D.Nodes of Ranvier
- 22 marks
The substance responsible for skin colour is referred to as
- A.Collagen
- B.Keratin
- C.Melanin
- D.Carotene
- 32 marks
Which of the following parts of the skeletal system protects the spinal cord?
- A.Skull Bones
- B.Sternum
- C.Vemor bone
- D.Vertebral column
- 42 marks
The type of sugar that is found in ribonucleic acid (RNA) is
- A.Deoxyribose
- B.Ribose
- C.Fructose
- D.Xylose
- 52 marks
If a tall pea plant (Tt) is crossed with a short pea plants (tt) the phonotypical ratio will be:
- A.0 : 2 tall to short
- B.3 : 1 tall to short
- C.1 : 1 tall to short
- D.2 : 2 tall to short
- 62 marks
The two main functions of human ear are ....
- A.Hearing and taste
- B.Hearing and balance
- C.Hearing and pressure
- D.Hearing and temperature
- 72 marks
Look at the figure below and then describe the type of gene mutation. Original sequence: A B C D E F G H. After mutation: A B C D G F E H.
- A.Inversion
- B.Deletion
- C.Duplication
- D.Translocation
- 82 marks
The nucleotides of each strand of DNA molecule are binded together by
- A.Hydrogen bond
- B.Phosphodiester bond
- C.Ionic bond
- D.Metallic bond
- 92 marks
The branch of biology that deals with the study of interactions between living organisms and their environment is called:
- A.Ecology
- B.Entomology
- C.Embryology
- D.Etiology
- 102 marks
Ali got cerebellum injury due to car accident, what are the effects that he is most likely to experience:
- A.Fluctuation of body temperature
- B.IncrEasing heart rate
- C.Loss of body balance and posture
- D.Decreasing heart rate
- 112 marks
The physiological inability of muscle to contract resulted of ATP depletion is termed
- A.Muscle fatigue
- B.Muscle tearing
- C.Muscle cramps
- D.Muscle strain
- 122 marks
The technique aimed to correct the mutated genes that cause human disease is
- A.Recombinant DNA
- B.Gene therapy
- C.Gene cloning
- D.Polymerase chain reaction
- 132 marks
Which one of the following set of terms is mismatched?
- A.Cranium and suture
- B.Wrist and pivot joint
- C.Shoulder and ball and socket join
- D.Knee and hinge joint
- 142 marks
If the sequence of (AGC) is a part of DNA, what is the complementary codon of mRNA?
- A.UCG
- B.GGC
- C.AGC
- D.GCU
- 152 marks
The neuron in the diagram below represents a:

- A.Multipolar neuron
- B.Anaxonic neuron
- C.Bipolar neuron
- D.Unipolar neuron
- 162 marks
Hormones that work together in pairs to regulate the level of critical substances are referred to as:
- A.Lipophilic hormones
- B.Steroid hormones
- C.Antagonistic hormones
- D.Non-steroid hormones
- 172 marks
The building block of nucleic acids (DNA and RNA) is
- A.AmiNo acids
- B.Fatty acids
- C.Deoxyribose
- D.Nucleotide
- 182 marks
The increasing concentration of toxic substances in an organisms as trophic level increase in a food chain or food web is described as:
- A.Biological magnification
- B.Biological concentration
- C.Biological accumulation
- D.Biological toxicity
- 192 marks
An enzyme that cuts DNA or genes into fragments is termed as:
- A.Isomerase
- B.Helicase
- C.Ligase
- D.Restriction
- 202 marks
The breeding of two closely related cows to increase milk production is said to be..
- A.Inbreeding
- B.Cross breeding
- C.Hybridization
- D.Crossing over
PART II: Match the terms in column A with suitable descriptions in column B (10 marks)
- M11 mark
Match the term in column A with the suitable description in column B: Fertilization. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M21 mark
Match the term in column A with the suitable description in column B: Mutation. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M31 mark
Match the term in column A with the suitable description in column B: Eutrophication. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M41 mark
Match the term in column A with the suitable description in column B: Foramen magnum. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M51 mark
Match the term in column A with the suitable description in column B: Transcription. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M61 mark
Match the term in column A with the suitable description in column B: Nondisjunction. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M71 mark
Match the term in column A with the suitable description in column B: Insulin. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M81 mark
Match the term in column A with the suitable description in column B: Hypothalamus. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M91 mark
Match the term in column A with the suitable description in column B: Myofibrils. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
- M101 mark
Match the term in column A with the suitable description in column B: Genome. Column B descriptions: members of a pair homologous chromosome do not separate; lowers the level of glucose when it becomes rise above normal; controls the output of hormones from pituitary gland; bundles of thread like structures found in skeletal muscles; an organism's complete set of genetic materials; union of male gamete (sperm) and female gamete (egg) to form a zygote; sudden change or error that occur in the genetic materials; excessive nutrients in the aquatic ecosystem that destroys the habitat of fish; large oval opening that locate at the base of the human skull; transfer of genetic instruction in specific gene into RNA molecule.
PART III: Use the information in the box below to fill the gaps (10 marks)
Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond
- F11 mark
The largest part of the brain is _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F21 mark
Too low growth hormone causes a condition referred to as _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F31 mark
The type of sugar that constitute DNA is _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F41 mark
The outermost layer of human skin is called _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F51 mark
In a food chain the trophic level of grazing animals can be categorized as primary _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F61 mark
The light-sensitive cells that are excited by low levels of light is _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F71 mark
The thick filamentous protein that constitute the skeletal muscle fibers is _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F81 mark
The bond that links amino acids in a protein is called _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F91 mark
The large scale study and cataloguing of the structure and function of proteins in the human body is called _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
- F101 mark
The upper limbs are connected to the axial skeleton by _____. (Words in the box: Epidermis, Rods, Cerebrum, Pectoral girdle, Deoxyribose, Dwarfism, Consumer, Proteomics, Myosin, Peptide bond.)
PART IV: Answer All of the Following Questions
- Q1a2 marks
Define the following terms: a) Genetic engineering
- Q1b2 marks
Define the following terms: b) Biodiversity
- Q24 marks
Identify the main parts of nervous system based on the flow chart given. Flow chart: Nervous system divides into [box 1] and Peripheral NS. [Box 1] divides into Brain and [box 2]. Peripheral NS divides into Sensory Division and [box 3]. [Box 3] divides into Autonomic NS and [box 4].

- Q34 marks
Ahmed has broken his leg in football match to the extent that his bone was protruding through his skin, identify the type of fracture.
- Q44 marks
Describe uses of DNA fingerprinting in our life?
- Q56 marks
Using a punnet square, find the phenotype ration of two heterozygote plants (Tt) for their F1 generation.
- Q63 marks
State the three structural parts of the nucleotide
- Q74 marks
Summarize the importance of DNA replication
- Q84 marks
The sequence of DNA strand is ACGTTG, Write the complementary strand of this DNA.
- Q93 marks
Mention at least three functions of the human skin
- Q104 marks
Differentiate between species diversity and genetic diversity?
Paper set by the Federal Ministry of Education, Culture and Higher Education (MoECHE), Somalia. Shared free of charge to help students prepare. The answers and explanations are written by Sheerxirfad teachers.




